Kniha Biosensing in Designed Proteins Pahan Godakumbura

Biosensing in Designed Proteins

Protein Mediated Biosensing Reaction with Quantum Dots Single Molecule Nanobiosensing Genetic Encoding of a Redox Cofactor into Designed Proteins

Jazyk: Angličtina
Vazba: Brožovaná
Vydavatel: VDM Verlag
Dostupnost: U nakladatele na objednávku
Odesíláme za 17-27 dnů
1 875
Biosensing in Designed Proteins provides a basic molecular approach to design biosensors in genetica...

Informace o knize

Jazyk
Angličtina
Vazba
Kniha - Brožovaná
Vydáno
2011
Stránek
276
EAN
9783639364194
ISBN
3639364198
Enbook ID
06843273
Vydavatel
Hmotnost
408
Rozměry
152 x 229 x 16

Kompletní popis

Biosensing in Designed Proteins provides a basic molecular approach to design biosensors in genetically modified proteins using electron transfer (ET) chemistry. The material is primarily aimed at probing the mechanistic insights into nanobiosensor performance using a library of metal complexes. The distance dependence of ET based biosensor which used ZnS coated CdSe (CdSe@ZnS) quantum dots (QDs) coupled with RuII complex modified MBP-MT function as a unimolecular nanobiosensor. The function of this protein-QD assembly is provided by ligand mediated protein motions that change the QD emission properties. This system operates using ET as opposed to energy transfer, with the metal complex as an electron donor, and the QD as an acceptor. The viability of the ET approach for biosensor development will also be outlined with respect to current mechanistic models.

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