Kniha Cancer Stem Cells O.D. Wiestler

Cancer Stem Cells

Novel Concepts and Prospects for Tumor Therapy

Jazyk: Angličtina
Vazba: Pevná
Dostupnost: Skladem u dodavatele
Odesíláme za 10-13 dnů
4 566
Cancer stem cells werehave originally been identified in leukemia and later in several solid tumor t...

Informace o knize

Jazyk
Angličtina
Vazba
Kniha - Pevná
Vydáno
2007
Stránek
263
EAN
9783540708520
ISBN
3540708529
Enbook ID
01568139
Hmotnost
577
Rozměry
155 x 235 x 22

Kompletní popis

Cancer stem cells werehave originally been identified in leukemia and later in several solid tumor types. They have very different properties from the bulk of the tumor, as they divide much more slowly and have very efficient drug- resistance mechanisms. Current treatments might largely spare cancer stem cells, thus leading to tumor recurrence and metastasis. The recent identification of growth and differentiation pathways responsible for cancer stem cell proliferation and survival will help in the discovery identification of novel therapeutic targets. Developing selective drugs against cancer stem cells offers great therapeutic opportunities but also provides for major challenges regarding preclinical models, therapeutic windows, and clinical study end points.

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