Kniha Chemical Carcinogenesis Francisco Feo

Chemical Carcinogenesis

Models and Mechanisms

Jazyk: Angličtina
Vazba: Brožovaná
Dostupnost: Skladem u dodavatele v malém množství
Odesíláme za 13-18 dnů
1 310
About two centuries after the communication by Sir Percival Pott that the "chimney sweeper disease"...

Informace o knize

Jazyk
Angličtina
Vazba
Kniha - Brožovaná
Vydáno
2013
Stránek
679
EAN
9781475796421
ISBN
1475796420
Enbook ID
02254307
Hmotnost
1303
Rozměry
178 x 254 x 38

Kompletní popis

About two centuries after the communication by Sir Percival Pott that the "chimney sweeper disease" was a cancer and its suggestion that active compounds of soot were the causative agents, and about one century after the description of urinary bladder cancer in dye workers, an enormous number of substances have been synthesized and have probably come into contact with man. Research in cancer prevention is of primary importance, and may receive continuous support from new discoveries on cancer etiology and pathogenesis. If one accepts the multistage model of chemical carcinogenesis, one has also to accept that many events occur between the contact of carcino genic compounds and their specific targets and the development of a clinically recognizable neoplasm. Thus, animal studies become essential to elucidate the different steps by which chemical carcinogens induce neoplasia. The analysis of these steps and the comparative evaluation of experimental models is essential to an understanding of pathogenesis.

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