Kniha Chitosan Vikas Rana

Chitosan

Modifications & Applications in Dosage Form Design

Autor: Vikas Rana
Jazyk: Angličtina
Vazba: Brožovaná
Dostupnost: 50 % šance
Prohledáme celý svět
1 370
Chitosan is the deacetylated form of chitin. Generally, the substance becomes soluble in dilute acid...

Informace o knize

Autor
Jazyk
Angličtina
Vazba
Kniha - Brožovaná
Vydáno
2011
Stránek
110
EAN
9781617611742
ISBN
9781617611742
Enbook ID
06426653
Hmotnost
182
Rozměry
159 x 229 x 7

Kompletní popis

Chitosan is the deacetylated form of chitin. Generally, the substance becomes soluble in dilute acids when the degree of deacetylation is more than 50%. The solubility of chitosan in dilute acids is often needed to be modified when specific drug release properties have to be tailored into the dosage form. The available toxicological data on chitosan and its modified forms appears to indicate its safety for oral use because high doses have been found to be tolerated well in rodents and rabbits. However, its local action as a haemostatic together with its ability to activate macrophages and cause cytokine release may require a careful assessment of its safety for parenteral use. This book offers the dynamics of chitosan''s detailed composition.

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