Development And Validation Of Analytical Methods

Name: Development And Validation Of Analytical Methods
Brand: LAP Lambert Academic Publishing
SKU: 9783659256097
Price: 1174 CZK
Availability: InStock

Simultaneous Estimation Of Amlodipine Besilate And Indapamide In Bulk Drug And Tablet Dosage Form

Autor: Mehul Patel, Rima Shah

Jazyk:

Vazba: Brožovaná

Vydavatel: LAP Lambert Academic Publishing

Dostupnost: U nakladatele na objednávku

Odesíláme za 17-27 dnů

1 174 Kč

Two UV-Spectrophotometric and RP-HPLC methods have been developed and validated for estimation of Am...

Informace o knize

Autor

Mehul Patel, Rima Shah

Jazyk

Angličtina

Vazba

Kniha - Brožovaná

Vydáno

2012

Stránek

100

EAN

9783659256097

Enbook ID

07045417

Vydavatel

LAP Lambert Academic Publishing

Hmotnost

165

Rozměry

150 x 220 x 6

Kompletní popis

Two UV-Spectrophotometric and RP-HPLC methods have been developed and validated for estimation of Amlodipine Besilate and Indapamide simultaneously.In absorbance correction method absorbance was measured at 360 nm for Amlodipine Besilate and at 242 nm for Indapamide. In First order Spectrophotometry method, the dA/d value in first order derivative spectra was measured at 242 nm for Amlodipine Besilate and 238 nm for Indapamide. The proposed methods were utilized for estimation of Amlodipine Besilate and Indapamide in tablet dosage form. RP-HPLC method showed adequate separation of Amlodipine Besilate and Indapamide. Amlodipine Besilate and Indapamide were estimated on C18 column using Acetonitrile: Water (contains 0.2% of Triethylamine and adjusting the pH to 4.0 with 10 % orthophosphoric acid) in a proportion of 70:30 v/v as mobile phase and detection was carried out at 238 nm. Results of Validation study and assay of all three methods were found to be satisfactory. The developed method were statistically compared using one way ANOVA which suggest that there is no significance difference among all three methods.

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Development And Validation Of Analytical Methods

Simultaneous Estimation Of Amlodipine Besilate And Indapamide In Bulk Drug And Tablet Dosage Form

Informace o knize

Kompletní popis

Mohlo by vás zajímat

Zákaznicí kteří koupili tuto knihu koupili také