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Kniha Dynamic-Clamp Alain Destexhe

Dynamic-Clamp

From Principles to Applications

Autor: Alain Destexhe, Thierry Bal
Jazyk: Angličtina
Vazba: Pevná
Vydavatel: Springer-Verlag New York Inc.
Dostupnost: Skladem u dodavatele v malém množství
Odesíláme za 13-18 dnů
5 079 Kč
Dynamic-clamp is a fascinating electrophysiology technique that consists of merging living neurons w...

Informace o knize

Autor
Alain Destexhe, Thierry Bal
Jazyk
Angličtina
Vazba
Kniha - Pevná
Vydáno
2009
Stránek
429
EAN
9780387892788
ISBN
0387892788
Enbook ID
01383375
Vydavatel
Springer-Verlag New York Inc.
Hmotnost
1760
Rozměry
155 x 235 x 35

Kompletní popis

Dynamic-clamp is a fascinating electrophysiology technique that consists of merging living neurons with computational models. The dynamic-clamp (also called conductance injection ) allows experimentalists and theoreticians to challenge neurons (or any other type of cell) with complex conductance stimuli generated by a computer.§The technique can be implemented from neural simulation environments and a variety of custom-made or commercial systems. The real-time interaction between the computer and cell also enables the design of recording paradigms with unprecedented accuracy via a computational model of the electrode. Dynamic-Clamp: From Principles to Applications contains contributions from leading researchers in the field, who investigate these paradigms at the cellular or network level, in vivo and in vitro, and in different brain regions and cardiac cells. Topics discussed include the addition of artificially-generated synaptic activity to neurons; adding, amplifying or neutralizing voltage-dependent conductances; creating hybrid networks with real and artificial cells; attaching simulated dendritic tree structures to the living cell; and connecting different neurons.§This book will be of interest to experimental biophysicists, neurophysiologists, and cardiac physiologists, as well as theoreticians, engineers, and computational neuroscientists. Graduate and undergraduate students will also find up-to-date coverage of physiological problems and how they are investigated.

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