Kniha Electronic DNA Detection Herman Pandana

Electronic DNA Detection

Carbon Nanotube Field Effect Transistors

Jazyk: Angličtina
Vazba: Brožovaná
Vydavatel: VDM Verlag
Dostupnost: Skladem u dodavatele
Odesíláme za 9-15 dnů
1 149
Spurred by the Human Genome Project, massive genetic §profiling of myriad diseases is being widely s...

Informace o knize

Jazyk
Angličtina
Vazba
Kniha - Brožovaná
Vydáno
2008
Stránek
96
EAN
9783639095418
ISBN
3639095413
Enbook ID
06818599
Vydavatel
Hmotnost
141
Rozměry
152 x 229 x 5

Kompletní popis

Spurred by the Human Genome Project, massive genetic §profiling of myriad diseases is being widely sought. §Despite high throughput and sensitivity the §conventional workhorses, i.e., micorarrays and bead-§based assays involve complicated protocols and §considerable expense due to the need for fluorescent §labeling. Consequently, their utility is limited §only to handful of well-endowed institutions. This §work attempts a low cost alternative suitable for §point-of-care facilities deployment. A method of §using biochips based on carbon nanotube field effect §transistor arrays is proposed and the feasibility of §using these sensors to detect the presence of §specific DNA sequences, e.g. expressed genes, in a §solution of DNA or RNA is demonstrated. This book §provides an extensive review of current available §DNA detection schemes, a detailed description of the §carbon nanotube transistors, including modeling, §fabrication and experimental setup, as well as §results that demonstrate the efficacy for DNA §detection. A section is also included describing a §low-cost protein detection scheme based on gold §nanoparticle surface plasmon resonant absorption.

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