Endothelial Dysfunction

Name: Endothelial Dysfunction
Brand: Nova Science Publishers Inc
SKU: 9781633212039
Price: 7280 CZK
Availability: InStock

Risk Factors, Role in Cardiovascular Diseases and Therapeutic Approaches

Autor: Trent H Keaton

Jazyk:

Vazba: Pevná

Vydavatel: Nova Science Publishers Inc

Dostupnost: 50 % šance

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The endothelium is a thin mono-cellular layer which covers the inner surface of the blood vessels, s...

Informace o knize

Autor

Trent H Keaton

Jazyk

Angličtina

Vazba

Kniha - Pevná

Vydáno

2014

Stránek

261

EAN

9781633212039

ISBN

9781633212039

Enbook ID

06429092

Vydavatel

Nova Science Publishers Inc

Hmotnost

684

Rozměry

183 x 260 x 21

Kompletní popis

The endothelium is a thin mono-cellular layer which covers the inner surface of the blood vessels, separating the circulating blood from the tissues and also has the responsibility for uninterrupted maintenance of circulation to all the vital tissues. Endothelium is a very active organ, it works as a receptor-effector organ and responds to each physical or chemical stimulus with the release of the appropriate substance with which it may maintain vasomotor balance and vascular-tissue homeostasis. It has the property of producing, independently, both agonistic and antagonistic substances that help to keep homeostasis and its function is not only autocrine, but also paracrine and endocrine. In this way it modulates the vascular smooth muscle cells producing relaxation or contraction, and therefore vasodilatation or vasoconstriction. The vascular endothelium is vulnerable to maximum wear and tear due to its positioning and requires prompt regeneration of the cells. Whenever the imbalance between substances with vasodilating, antimitogenic, and antithrombogenic properties and substances with vasoconstricting, prothrombotic and proliferative characteristics takes place, it causes a pathological condition known as endothelial dysfunction. These substances intervenes in cell proliferation and migration, in leukocyte adhesion and activation and in immunological and inflammatory processes, further which is responsible for apoptosis of vascular endothelial cells resulting in overall endothelial dysfunction and vasculopathy. This book discusses, in further detail, the risk factors, and the role of endothelial dysfunction in cardiovascular diseases and therapeutic approaches to dealing with endothelial dysfunction.

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Endothelial Dysfunction

Risk Factors, Role in Cardiovascular Diseases and Therapeutic Approaches

Informace o knize

Kompletní popis

Mohlo by vás zajímat

Zákaznicí kteří koupili tuto knihu koupili také