Kniha Engineering Genetic Logic Gates Baojun Wang

Engineering Genetic Logic Gates

Design and Functional Assembly of Synthetic Biological Circuits

Autor: Baojun Wang
Jazyk: Angličtina
Vazba: Brožovaná
Dostupnost: Skladem u dodavatele
Odesíláme za 5-8 dnů
1 555
Programming living cells with synthetic gene circuits to perform desired tasks has been a major them...

Informace o knize

Autor
Jazyk
Angličtina
Vazba
Kniha - Brožovaná
Vydáno
2012
Stránek
208
EAN
9783659274794
Enbook ID
07012430
Hmotnost
326
Rozměry
150 x 220 x 12

Kompletní popis

Programming living cells with synthetic gene circuits to perform desired tasks has been a major theme in the growing field of synthetic biology. However, gene circuit engineering currently lacks the same predictability and reliability as seen in other mature engineering disciplines. This book introduces the design methodology for engineering novel modular and orthogonal genetic logic devices, and the predictable functional assembly of modular biological components into customisable biological circuits. Various genetic logic devices, including AND, NOT and NAND gates, were constructed in Escherichia coli bacteria to achieve customised cellular computing and sensing. An effective parts-based engineering approach is presented for assembling individual biological parts into functional circuits using engineered in-context characterised modules aided by modelling. The book is a pioneering work in the field, and should be useful for engineers who would like to engineer synthetic biological systems for human desired purposes and for biologists who are interested in the design principles of natural biological circuits.

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