Kniha Gene Essentiality Long Jason Lu

Gene Essentiality

Methods and Protocols

Autor: Long Jason Lu
Jazyk: Angličtina
Vazba: Pevná
Vydavatel: Humana Press Inc.
Dostupnost: Skladem u dodavatele v malém množství
Odesíláme za 13-18 dnů
2 567
This volume opens by covering two main types of approaches widely used to determine essential genes:...

Informace o knize

Jazyk
Angličtina
Vazba
Kniha - Pevná
Vydáno
2015
Stránek
248
EAN
9781493923977
ISBN
1493923978
Enbook ID
09104752
Vydavatel
Hmotnost
6952
Rozměry
178 x 254 x 262

Kompletní popis

This volume opens by covering two main types of approaches widely used to determine essential genes: single-gene knockouts and transposon mutagenesis, in both prokaryotes and Candida albicans . Given the significant advancement in the computational predictions of microbial essential genes, the second half of the book examines four main types of approaches: comparative genomics, supervised machine learning, constraint-based methods, and corrections of transposon mutagenesis data, as well as databases and servers that are often used in studying gene essentiality. Written in the highly successful Methods in Molecular Biology series format, chapters include an introduction to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.§§Authoritative and up-to-date, Gene Essentiality: Methods and Protocols will aid researchers who wish to further our knowledge in this vital field of study.§

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