Kniha Gene Prioritization Ali Masoudi-Nejad

Gene Prioritization

Rationale, Methodologies and Algorithms

Jazyk: Angličtina
Vazba: Brožovaná
Vydavatel: Springer, Berlin
Dostupnost: 50 % šance
Prohledáme celý svět
1 344
Identifying causal genes underlying susceptibility to human disease is a problem of primary importan...

Informace o knize

Jazyk
Angličtina
Vazba
Kniha - Brožovaná
Vydáno
2014
Stránek
66
EAN
9783319046860
ISBN
3319046861
Enbook ID
02432595
Vydavatel
Hmotnost
140
Rozměry
140 x 239 x 6

Kompletní popis

Identifying causal genes underlying susceptibility to human disease is a problem of primary importance in the post-genomic era and in current biomedical research. Recently, there has been a paradigm shift of such gene-discovery efforts from rare, monogenic conditions to common oligogenic or multifactorial conditions such as asthma, diabetes, cancers and neurological disorders. These conditions are referred to as multifactorial because, susceptibility to these diseases is attributed to the combinatorial effects of genetic variation at a number of different genes and their interaction with relevant environmental exposures. The goal of this book is to introduce gene prioritization aspects and the candidate gene prioritization algorithms to give readers a comprehensive view on the subject.

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