Kniha Mapping Genetic Interactions Andrew Freywald

Mapping Genetic Interactions

Jazyk: Angličtina
Vazba: Pevná
Vydavatel: Springer US
Dostupnost: Skladem u dodavatele
Odesíláme za 10-13 dnů
4 461
This volume details methods of identifying synthetic lethal, genetic interactions by various approac...

Informace o knize

Jazyk
Angličtina
Vazba
Kniha - Pevná
Vydáno
2021
Stránek
380
EAN
9781071617397
ISBN
1071617397
Enbook ID
35719578
Vydavatel
Hmotnost
910
Rozměry
183 x 260 x 26

Kompletní popis

This volume details methods of identifying synthetic lethal, genetic interactions by various approaches in different model systems including human cancer cells. Chapters guide readers through genetic interactions in model organisms, RNA interference, CRISPR/Cas9 based genome editing technologies, drug-gene interactions, mapping chemical genetic interactions, synergistic drug-gene relations, single cell sequencing, gene expression profiling, and novel genetic interactions. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Genetic Interaction Mapping aims to be a useful practical guide to researches to help further their study in this field.

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