Kniha GLIPIZIDE EXTENDED RELEASE MATRIX TABLET Ashish Mane

GLIPIZIDE EXTENDED RELEASE MATRIX TABLET

Design and In vitro Evaluation of Extended Release Glipizide Matrix Tablet

Jazyk: Angličtina
Vazba: Brožovaná
Dostupnost: Skladem u dodavatele
Odesíláme za 8-11 dnů
967
The main goal of present study was formulation and in vitro evaluation extended release tablets of g...

Informace o knize

Jazyk
Angličtina
Vazba
Kniha - Brožovaná
Vydáno
2012
Stránek
120
EAN
9783659234422
Enbook ID
07004980
Hmotnost
195
Rozměry
150 x 220 x 7

Kompletní popis

The main goal of present study was formulation and in vitro evaluation extended release tablets of glipizide.In this tablets glipizide was used as drug which is effective in management of diabetes for period of 12 hrs,which will increase patient compliance and be economical to the patient.Extended release tablets were prepared using polymer HPMC K4M, HPMC K15M, HPMC K100M with suitable excipients.Tablets showed initial release to initiate pharmacological action and slowing releasing drug to maintain therapeutic action.Prepared tablets were evaluated for thickness, hardness, friability, uniformity of weight, swelling property, drug content uniformity and dissolution study.Disintegration time and drug release were taken as basis to optimise the tablets.Accelerated stability study for optimised batch was also performed.

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