Kniha GPCRs Beata Jastrzebska

GPCRs

Structure, Function, and Drug Discovery

Jazyk: Angličtina
Vazba: Brožovaná
Vydavatel: Elsevier Books
Dostupnost: U nakladatele na objednávku
Odesíláme za 28-34 dnů
4 405
GPCRS: Structure, Function, and Drug Discovery provides a comprehensive overview of recent discoveri...

Informace o knize

Jazyk
Angličtina
Vazba
Kniha - Brožovaná
Vydáno
2019
Stránek
500
EAN
9780128162286
ISBN
0128162287
Enbook ID
22120894
Vydavatel
Hmotnost
1310
Rozměry
216 x 276 x 27

Kompletní popis

GPCRS: Structure, Function, and Drug Discovery provides a comprehensive overview of recent discoveries and our current understanding of GPCR structure, signaling, physiology, pharmacology and methods of study. In addition to the fundamental aspects of GPCR function and dynamics, international experts discuss crystal structures, GPCR complexes with partner proteins, GPCR allosteric modulation, biased signaling through protein partners, deorphanization of GPCRs, and novel GPCR-targeting ligands that could lead to the development of new therapeutics against human diseases. GPCR association with, and possible therapeutic pathways for, retinal degenerative diseases, Alzheimer’s disease, Parkinson’s disease, cancer and diabetic nephropathy, among other illnesses, are examined in-depth. Addresses our current understanding and novel advances in the GPCR field, directing readers towards recent finding of key significance for translational medicineCombines a thorough discussion of structure and function of GPCRs with disease association and drug discoveryFeatures chapter contributions from international experts in GPCR structure, signaling, physiology and pharmacology

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