Histone Recognition

Name: Histone Recognition
Brand: Springer International Publishing AG
SKU: 9783319181011
Price: 2567 CZK
Availability: InStock

Autor: Ming-Ming Zhou

Jazyk:

Vazba: Pevná

Vydavatel: Springer International Publishing AG

Dostupnost: Skladem u dodavatele v malém množství

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2 567 Kč

This book provides a timely review of the role of histone modifications in epigenetic control of gen...

Informace o knize

Autor

Ming-Ming Zhou

Jazyk

Angličtina

Vazba

Kniha - Pevná

Vydáno

2015

Stránek

282

EAN

9783319181011

ISBN

3319181017

Enbook ID

09255758

Vydavatel

Springer International Publishing AG

Hmotnost

720

Rozměry

155 x 235 x 243

Kompletní popis

This book provides a timely review of the role of histone modifications in epigenetic control of gene expression. Topics covered include: basic mechanisms of molecular recognition of histone post-translational modification (PTMs); combinatorial readout of histone PTMs by tandem epigenome reader domains; genome-wide profiling of histone PTM interactions; small molecule modulation of histone PTM interactions and their potential as a new approach to therapeutic intervention in human diseases. All chapters were written by leading scientists who made the original key discoveries of the structure and mechanism of evolutionarily conserved reader domains, which serve to direct gene transcription in chromatin through interactions with DNA-packing histones in a PTM-sensitive manner.§

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Histone Recognition

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