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Kniha Histone Recognition Ming-Ming Zhou

Histone Recognition

Autor: Ming-Ming Zhou
Jazyk: Angličtina
Vazba: Brožovaná
Vydavatel: Springer International Publishing AG
Dostupnost: Skladem u dodavatele
Odesíláme za 5-8 dnů
2 286 Kč
This book provides a timely review of the role of histone modifications in epigenetic control of gen...

Informace o knize

Autor
Ming-Ming Zhou
Jazyk
Angličtina
Vazba
Kniha - Brožovaná
Vydáno
2016
Stránek
282
EAN
9783319376660
ISBN
3319376667
Enbook ID
15194239
Vydavatel
Springer International Publishing AG
Hmotnost
4453
Rozměry
155 x 235 x 16

Kompletní popis

This book provides a timely review of the role of histone modifications in epigenetic control of gene expression. Topics covered include: basic mechanisms of molecular recognition of histone post-translational modification (PTMs); combinatorial readout of histone PTMs by tandem epigenome reader domains; genome-wide profiling of histone PTM interactions; small molecule modulation of histone PTM interactions and their potential as a new approach to therapeutic intervention in human diseases. All chapters were written by leading scientists who made the original key discoveries of the structure and mechanism of evolutionarily conserved reader domains, which serve to direct gene transcription in chromatin through interactions with DNA-packing histones in a PTM-sensitive manner.

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