Kniha Immunological Synapse Takashi Saito

Immunological Synapse

Jazyk: Angličtina
Vazba: Pevná
Dostupnost: Skladem u dodavatele
Odesíláme za 10-13 dnů
3 426
While the importance of the immune synapse as a dynamic cell junction that regulates intercellular c...

Informace o knize

Jazyk
Angličtina
Vazba
Kniha - Pevná
Vydáno
2009
Stránek
255
EAN
9783642038570
ISBN
3642038573
Enbook ID
01650366
Hmotnost
626
Rozměry
155 x 235 x 21

Kompletní popis

While the importance of the immune synapse as a dynamic cell junction that regulates intercellular communication and viral transmission is universally recognized, many of quantitative and qualitative details remain unsettled. The plasticity of this cell junction has to accommodate many very different binding partners and control the fate of interacting cells. It is likely that developmental changes in the state of the T cells or the APCs can impact the structure of the synapse. It is hoped that uncovering the ordered molecular rearrangement at the membrane will provide the long sought after clues for the remarkable functional sensitivity of T lymphocytes. These dynamic molecular interactions may eventually explain how engagement of the same TCR can generate different outcomes that resolve the immune challenges. The reviews in this issue present a broad slice of the many diverse topics that are currently intensely debated.

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