Kniha Inflammatory Disorders Mieczyslaw Pokorski

Inflammatory Disorders

Jazyk: Angličtina
Vazba: Pevná
Dostupnost: Skladem u dodavatele
Odesíláme za 10-13 dnů
2 286
The mechanistic basis of chronic inflammation remains unclear. The research sheds new light on the i...

Informace o knize

Jazyk
Angličtina
Vazba
Kniha - Pevná
Vydáno
2014
Stránek
67
EAN
9783319100111
ISBN
3319100114
Enbook ID
05153417
Hmotnost
404
Rozměry
178 x 254 x 10

Kompletní popis

The mechanistic basis of chronic inflammation remains unclear. The research sheds new light on the immune cells expressing the activation markers HLA-DR and regulatory T cells (Tregs) and the cells expressing Siglec receptors as being key players in the immune system responsiveness to antigens and thus in lung tissue damage of chronic inflammation. The results help understand the mechanisms of action of common drugs used in COPD, such as formoterol, tiotropium, or corticosteroids, and point to novel drug targets. The chapters also deal with brain damaging effects, by far unrecognized, of inhaled corticosteroid therapy, a time-proven management of chronic inflammatory airway conditions; asthma being a case in point. Novel methods, likely less producing side effects, of macrolide antibiotics administration by inhalation are discussed, emphasizing not only bacteriostatic but also anti-inflammatory action.

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