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Kniha Inflammatory Pathways in Diabetes Michael Pugia

Inflammatory Pathways in Diabetes

Biomarkers and Clinical Correlates

Autor: Michael Pugia
Jazyk: Angličtina
Vazba: Pevná
Vydavatel: Springer International Publishing AG
Dostupnost: Skladem u dodavatele
Odesíláme za 10-13 dnů
2 286 Kč
This book discusses recent advances in new anti- and pro-inflammatory pathways in diabetic disease,...

Informace o knize

Autor
Michael Pugia
Jazyk
Angličtina
Vazba
Kniha - Pevná
Vydáno
2015
Stránek
219
EAN
9783319219264
ISBN
331921926X
Enbook ID
09378352
Vydavatel
Springer International Publishing AG
Hmotnost
5221
Rozměry
155 x 235 x 242

Kompletní popis

This book discusses recent advances in new anti- and pro-inflammatory pathways in diabetic disease, and identifies new diagnostic immunological methods that offer potential companion diagnostics for diabetic diseases. New methods in proteomics, mass spectroscopy, immunological assay design, measurement of cellular signal transduction and protease inhibition are used to clarify new biochemical pathways. Biomarker validation in animal models and correlations in humans for diagnostic clinical trials shed new light on the impact of diabetic diseases. The book reviews current understanding of inflammatory pathways in the pathophysiology of insulin resistance, metabolic syndrome, nephritis and other diabetic inflammatory conditions, and is the first to describe the impact of novel adipokines, protease inhibitors and complement markers. By presenting new methodologies for biomarker discovery, it provides a valuable resource for researchers studying clinical diagnosis, drug development, bio-analytical chemistry, proteomics and biochemistry. It is also useful for those conducting clinical and biological studies for targeted drug development. The methodologies and approaches can be applied to other markers, and the information will be helpful in the preparation of research grant applications.§

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