Information-Theoretic Evaluation for Computational Biomedical Ontologies

Name: Information-Theoretic Evaluation for Computational Biomedical Ontologies
Brand: Springer International Publishing AG
SKU: 9783319041377
Price: 1147 CZK
Availability: InStock

Autor: Wyatt Travis Clark

Jazyk:

Vazba: Brožovaná

Vydavatel: Springer International Publishing AG

Dostupnost: Skladem u dodavatele

Odesíláme za 5-8 dnů

1 147 Kč

The development of effective methods for the prediction of ontological annotations is an important g...

Informace o knize

Autor

Wyatt Travis Clark

Jazyk

Angličtina

Vazba

Kniha - Brožovaná

Vydáno

2014

Stránek

EAN

9783319041377

ISBN

3319041371

Enbook ID

05266897

Vydavatel

Springer International Publishing AG

Hmotnost

1007

Rozměry

155 x 235 x 7

Kompletní popis

The development of effective methods for the prediction of ontological annotations is an important goal in computational biology, yet evaluating their performance is difficult due to problems caused by the structure of biomedical ontologies and incomplete annotations of genes. This work proposes an information-theoretic framework to evaluate the performance of computational protein function prediction. A Bayesian network is used, structured according to the underlying ontology, to model the prior probability of a protein's function. The concepts of misinformation and remaining uncertainty are then defined, that can be seen as analogs of precision and recall. Finally, semantic distance is proposed as a single statistic for ranking classification models. The approach is evaluated by analyzing three protein function predictors of gene ontology terms. The work addresses several weaknesses of current metrics, and provides valuable insights into the performance of protein function prediction tools.

Mohlo by vás zajímat

Zákaznicí kteří koupili tuto knihu koupili také

Nejčastěji hledané

Categories

Authors

Publishers

Produkty

Produkty

Nejčastěji hledané

Categories

Authors

Publishers

Produkty

Produkty

Information-Theoretic Evaluation for Computational Biomedical Ontologies

Informace o knize

Kompletní popis

Mohlo by vás zajímat

Zákaznicí kteří koupili tuto knihu koupili také