Kniha Integrin-mediated Interactions between Cells and Biomimetic Materials Robert Knerr

Integrin-mediated Interactions between Cells and Biomimetic Materials

Autor: Robert Knerr
Jazyk: Angličtina
Vazba: Brožovaná
Dostupnost: Skladem u dodavatele
Odesíláme za 14-21 dnů
1 833
Based on the idea of self-assembled monolayers of alkanethiols on gold, it was the goal of this thes...

Informace o knize

Autor
Jazyk
Angličtina
Vazba
Kniha - Brožovaná
Vydáno
2008
Stránek
232
EAN
9783639042009
ISBN
363904200X
Enbook ID
06813792
Hmotnost
345
Rozměry
152 x 229 x 12

Kompletní popis

Based on the idea of self-assembled monolayers of alkanethiols on gold, it was the goal of this thesis to develop a versatile model system for an efficient and straightforward characterization of cell - biomaterial interactions on PEG-rich surfaces. The necessary compounds for this model system should allow for mimicking the surface of polymeric poly(ethyleneglycol)-rich biomaterials used for the design of cell carriers. By evaluating the adsorption of proteins and the adhesion characteristics of mammalian cells on these artificial surfaces, conclusions can be drawn, on how polymers should be engineered to achieve an optimal adhesion, growth or proliferation of cells. In particular, the consequences of an attachment of peptidic cell adhesion peptides and growth factors had to be elucidated.

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