Kniha Kinase Screening and Profiling Said A. Goueli

Kinase Screening and Profiling

Methods and Protocols

Jazyk: Angličtina
Vazba: Brožovaná
Vydavatel: Humana Press Inc.
Dostupnost: Skladem u dodavatele
Odesíláme za 5-8 dnů
2 122
This volume focuses on screening and profiling kinase inhibitors or activators. Chapters in this boo...

Informace o knize

Jazyk
Angličtina
Vazba
Kniha - Brožovaná
Vydáno
2016
Stránek
223
EAN
9781493949236
ISBN
1493949233
Enbook ID
18049989
Vydavatel
Hmotnost
4511
Rozměry
178 x 254 x 13

Kompletní popis

This volume focuses on screening and profiling kinase inhibitors or activators. Chapters in this book cover several facets of the drug discovery processes starting with target identification, and assay development and screening chemical libraries for hit identification and lead optimization. The profiling portion of Kinase Screening and Profiling: Methods and Protocols discusses several strategies and techniques that are required to minimize off target hits and reduce cellular toxicities that are caused by liability kinases. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Timely and authoritative, Kinase Screening and Profiling: Methods and Protocols, will benefit scientists and researchers who are interested in exploring the role of kinases in academic, as well as pharmaceutical research.

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