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Kniha Myocardial Tissue Engineering Aldo R. Boccaccini

Myocardial Tissue Engineering

Autor: Aldo R. Boccaccini, Sian E. Harding
Jazyk: Angličtina
Vazba: Pevná
Vydavatel: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Dostupnost: Skladem u dodavatele
Odesíláme za 10-13 dnů
3 426 Kč
Myocardial tissue engineering (MTE), a concept that intends to prolong patients life after cardiac d...

Informace o knize

Autor
Aldo R. Boccaccini, Sian E. Harding
Jazyk
Angličtina
Vazba
Kniha - Pevná
Vydáno
2011
Stránek
270
EAN
9783642180552
ISBN
3642180558
Enbook ID
01657286
Vydavatel
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Hmotnost
588
Rozměry
155 x 235 x 18

Kompletní popis

Myocardial tissue engineering (MTE), a concept that intends to prolong patients life after cardiac damage by supporting or restoring heart function, is continuously improving. Common MTE strategies include an engineered vehicle , which may be a porous scaffold or a dense substrate or patch, made of either natural or synthetic polymeric materials. The function of the substrate is to aid transportation of cells into the diseased region of the heart and support their integration. This book, which contains chapters written by leading experts in MTE, gives a complete analysis of the area and presents the latest advances in the field. The chapters cover all relevant aspects of MTE strategies, including cell sources, specific TE techniques and biomaterials used. Many different cell types have been suggested for cell therapy in the framework of MTE, including autologous bone marrow-derived or cardiac progenitors, as well as embryonic or induced pluripotent stem cells, each having their particular advantages and disadvantages. The book covers a complete range of biomaterials, examining different aspects of their application in MTE, such as biocompatibility with cardiac cells, mechanical capability and compatibility with the mechanical properties of the native myocardium as well as degradation behaviour in vivo and in vitro. Although a great deal of research is being carried out in the field, this book also addresses many questions that still remain unanswered and highlights those areas in which further research efforts are required. The book will also give an insight into clinical trials and possible novel cell sources for cell therapy in MTE.

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