Kniha Nuclear Factor  B R. Beyaert

Nuclear Factor B

Regulation and Role in Disease

Autor: R. Beyaert
Jazyk: Angličtina
Vazba: Brožovaná
Vydavatel: Springer
Dostupnost: Skladem u dodavatele v malém množství
Odesíláme za 13-18 dnů
2 567
The transcription factor NF-kappaB and the signaling pathways regulating its activity constitute a p...

Informace o knize

Autor
Jazyk
Angličtina
Vazba
Kniha - Brožovaná
Vydáno
2012
Stránek
426
EAN
9789401039833
ISBN
9401039836
Enbook ID
02184486
Vydavatel
Hmotnost
698
Rozměry
160 x 240 x 24

Kompletní popis

The transcription factor NF-kappaB and the signaling pathways regulating its activity constitute a paradigm of membrane to nucleus communication. NF-kappaB is central to a number of cellular functions including cell proliferation, apoptosis, and cellular differentiation. This transcription factor also plays essential roles in innate and acquired immunity, and its deregulation leads to important human diseases such as inflammation and cancer. Therefore NF-kappaB, together with the signaling pathways leading to its activation, constitute an attractive therapeutic target. §This book is the first to review and synthesize our knowledge on this interesting transcription factor. It will be of great interest for those entering or already actively working in the NF-kappaB field, as well as a valuable reference for students, established researchers, or clinicians with wider interests in the fields of molecular cell biology and biomedicine.

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