p53

Name: p53
Brand: Springer-Verlag New York Inc.
SKU: 9781441982308
Price: 4022 CZK
Availability: InStock

Autor: Ayeda Ayed, Theodore Hupp

Jazyk:

Vazba: Pevná

Vydavatel: Springer-Verlag New York Inc.

Dostupnost: U nakladatele na objednávku

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This volume, p53, was developed primarily as a resource for access to key ideas in the field that ha...

Informace o knize

Autor

Ayeda Ayed, Theodore Hupp

Jazyk

Angličtina

Vazba

Kniha - Pevná

Vydáno

2010

Stránek

200

EAN

9781441982308

ISBN

1441982302

Enbook ID

01424399

Vydavatel

Springer-Verlag New York Inc.

Hmotnost

419

Rozměry

161 x 236 x 18

Kompletní popis

This volume, p53, was developed primarily as a resource for access to key ideas in the field that have developed over the years including how transgenics have been used to study p53, how clinical genetics have identified and studied mutations in p53 found in human cancers, how p53 can be regulated by post-translational modification, and how key drug targets have been defined, namely MDM2, which has provided fundamental approaches for defining how p53 can be activated with potentially therapeutic effect. The key concepts in the chapters included provide a perspective on key paradigms in the p53 field.

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Kompletní popis

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