Peptidomimetics Protocols

Name: Peptidomimetics Protocols
Brand: Humana Press Inc.
SKU: 9780896035171
Price: 2286 CZK
Availability: InStock

Autor: Wieslaw M. Kazmierski

Jazyk:

Vazba: Pevná

Vydavatel: Humana Press Inc.

Dostupnost: Skladem u dodavatele

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2 286 Kč

A state-of-the-art collection of detailed synthetic procedures that lead to a variety of scaffolds,...

Informace o knize

Autor

Wieslaw M. Kazmierski

Jazyk

Angličtina

Vazba

Kniha - Pevná

Vydáno

1998

Stránek

549

EAN

9780896035171

ISBN

0896035174

Enbook ID

01400753

Vydavatel

Humana Press Inc.

Hmotnost

2260

Rozměry

155 x 235 x 36

Kompletní popis

A state-of-the-art collection of detailed synthetic procedures that lead to a variety of scaffolds, turn mimetics, peptide-bound replacements, and enzyme inhibitors. Topics range from unusual syntheses of amino acids to the use of a variety of linear and heterocyclic scaffolds in place of the peptide backbone. Important chemical procedures and methods include the transient protection of charged peptides as neutral prodrugs for improved blood-brain penetration and the replacement of peptide bonds with heterocyclic rings, olefins and fluoroolefins, and ketomethylenes. Synthetic protocols towards the transition-state mimics and reactive "warheads," applicable in enzyme inhibitors, are also disclosed.

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