Pharmacokinetic-Pharmacodynamic Modeling and Simulation

Name: Pharmacokinetic-Pharmacodynamic Modeling and Simulation
Brand: Springer, Berlin
SKU: 9781441938961
Price: 1975 CZK
Availability: InStock

Autor: Peter L. Bonate

Jazyk:

Vazba: Brožovaná

Vydavatel: Springer, Berlin

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This book presents both the art and science behind pharmacokinetic-pharmacodynamic modeling. Using a...

Informace o knize

Autor

Peter L. Bonate

Jazyk

Angličtina

Vazba

Kniha - Brožovaná

Vydáno

2010

Stránek

387

EAN

9781441938961

Enbook ID

01422444

Vydavatel

Springer, Berlin

Hmotnost

997

Rozměry

216 x 279

Kompletní popis

This book presents both the art and science behind pharmacokinetic-pharmacodynamic modeling. Using a building-block approach, the author starts from linear and nonlinear models at the individual level and proceeds to develop more complex linear and nonlinear mixed effects models at the population level, with particular emphasis on showing the interrelationships between the various model types. The theory behind the methods are illustrated using real data drawn from the literature and from the author s own experiences in drug development. Data are analyzed using a variety of software, including SAS, WinNonlin, SAAM II, and NONMEM. A key component of the book is to show how models are accepted and rejected, ultimately leading to a useful and informative model that can be utilized using computer simulation to answer "what-if" questions.

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Pharmacokinetic-Pharmacodynamic Modeling and Simulation

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