Physics at the Biomolecular Interface

Name: Physics at the Biomolecular Interface
Brand: Springer International Publishing AG
SKU: 9783319308517
Price: 2286 CZK
Availability: InStock

Fundamentals for Molecular Targeted Therapy

Autor: Ariel Fernandez

Jazyk:

Vazba: Pevná

Vydavatel: Springer International Publishing AG

Dostupnost: Skladem u dodavatele

Odesíláme za 10-13 dnů

2 286 Kč

This book§focuses primarily on the role of interfacial forces in understanding biological§phenomena...

Informace o knize

Autor

Ariel Fernandez

Jazyk

Angličtina

Vazba

Kniha - Pevná

Vydáno

2016

Stránek

483

EAN

9783319308517

ISBN

3319308513

Enbook ID

02930308

Vydavatel

Springer International Publishing AG

Hmotnost

8749

Rozměry

155 x 235 x 34

Kompletní popis

This book§focuses primarily on the role of interfacial forces in understanding biological§phenomena at the molecular scale. By providing a suitable statistical§mechanical apparatus to handle the biomolecular interface, the book becomes§uniquely positioned to address core problems in molecular biophysics. It§highlights the importance of interfacial tension in delineating a solution to§the protein folding problem, in unravelling the physico-chemical basis of§enzyme catalysis and protein associations, and in rationally designing§molecular targeted therapies. Thus grounded in fundamental science, the book§develops a powerful technological platform for drug discovery, while it is set§to inspire scientists at any level in their careers determined to address the§major challenges in molecular biophysics.§§The§acknowledgment of how exquisitely the structure and dynamics of proteins and their§aqueous environment are related attests to the overdue recognition that§biomolecular phenomena cannot be effectively understood without dealing with§interfacial behaviour. There is an urge to grasp how biologically relevant§behaviour is shaped by the structuring of biomolecular interfaces and how§interfacial tension affects the molecular events that take place in the cell.§This book squarely addresses these needs from a physicist perspective.§§The§book may serve as a monograph for practitioners and, alternatively, as an§advanced textbook. Fruitful reading requires a background in physical chemistry§and some basics in biophysics. The selected problems at the end of the chapters§and the progression in conceptual difficulty make it a suitable textbook for a§graduate level course or an elective course for seniors majoring in chemistry,§physics, biomedical engineering or related disciplines.

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Physics at the Biomolecular Interface

Fundamentals for Molecular Targeted Therapy

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