Post-Structural Genomics

Name: Post-Structural Genomics
Brand: VDM Verlag
SKU: 9783639113167
Price: 1377 CZK
Availability: InStock

Correlate Protein Sequence, Structure, and Function

Autor: Zhiyan Fu

Jazyk:

Vazba: Brožovaná

Vydavatel: VDM Verlag

Dostupnost: Skladem u dodavatele

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1 377 Kč

One of the goals the post-genomic era is to use§protein sequence and structure data to learn about§t...

Informace o knize

Autor

Zhiyan Fu

Jazyk

Angličtina

Vazba

Kniha - Brožovaná

Vydáno

2008

Stránek

132

EAN

9783639113167

ISBN

3639113160

Enbook ID

06820202

Vydavatel

VDM Verlag

Hmotnost

194

Rozměry

155 x 227 x 9

Kompletní popis

One of the goals the post-genomic era is to use§protein sequence and structure data to learn about§the function of these proteins in normal and disease§states. In the omics era, computational methods§constitute a valuable tool, because they can easily§process large amounts of data and provide useful and§instant information relevant in biomedical research.§This book described using computational approaches to§study the effects of genetic mutations in proteins,§with the general aim of correlating protein sequence,§structure, and function. Our works focus on§identifying whether genotype/phenotype relationship§can be learned from protein sequence and structuralinformation, whether protein structure prediction§methods are accurate enough to provide useful§information when the experimental structures are not§available, and finally to combine this information to§predict and understand the effect of mutations on§clinical phenotype and drug responses. The approaches§developed in this work enable a systematic,§comprehensive, and quantitative analysis of§disease-related mutations and establish a paradigm to§study genotype/phenotype correlations.

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Post-Structural Genomics

Correlate Protein Sequence, Structure, and Function

Informace o knize

Kompletní popis

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Zákaznicí kteří koupili tuto knihu koupili také