Probability Models for DNA Sequence Evolution

Name: Probability Models for DNA Sequence Evolution
Brand: Springer-Verlag New York Inc.
SKU: 9780387781686
Price: 4425 CZK
Availability: InStock

Autor: Richard Durrett

Jazyk:

Vazba: Pevná

Vydavatel: Springer-Verlag New York Inc.

Dostupnost: Skladem u dodavatele

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4 425 Kč

As a starting point the authors address the fundamental question "What underlying forces are respons...

Informace o knize

Autor

Richard Durrett

Jazyk

Angličtina

Vazba

Kniha - Pevná

Vydáno

2008

Stránek

431

EAN

9780387781686

ISBN

0387781684

Enbook ID

01247776

Vydavatel

Springer-Verlag New York Inc.

Hmotnost

614

Rozměry

164 x 244 x 30

Kompletní popis

As a starting point the authors address the fundamental question "What underlying forces are responsible for the observed patterns of variability, given a collection of DNA sequences?" In approaching this question they introduce and analyze a number of probability models: the Wright-Fisher model, the coalescent, the infinite alleles model, and the infinite sites model. They then discuss the complications that come from nonconstant population size, recombination, population subdivision, and three forms of natural selection: directional selection, balancing selection, and background selection. These theoretical results set the stage for the investigation of various statistical tests to detect departures from "neutral evolution."

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Probability Models for DNA Sequence Evolution

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