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Kniha PTEN Leonardo Salmena

PTEN

Methods and Protocols

Autor: Leonardo Salmena, Vuk Stambolic
Jazyk: Angličtina
Vazba: Brožovaná
Vydavatel: Humana Press Inc.
Dostupnost: Skladem u dodavatele
Odesíláme za 10-18 dnů
2 561 Kč
This volume provides detailed descriptions of prevailing and novel techniques used by experts in the...

Informace o knize

Autor
Leonardo Salmena, Vuk Stambolic
Jazyk
Angličtina
Vazba
Kniha - Brožovaná
Vydáno
2019
Stránek
324
EAN
9781493980154
Enbook ID
21063879
Vydavatel
Humana Press Inc.
Hmotnost
640
Rozměry
178 x 254 x 19

Kompletní popis

This volume provides detailed descriptions of prevailing and novel techniques used by experts in the study of PTEN function in disease and biology. The book begins with chapters exploring methods to detect expression levels of PTEN in normal and diseased human specimens; methods to evaluate specific PTEN function in brain cancer; methods that utilize a new biosensor to measure PTEN regulation; and techniques to measure post-transcriptional regulation of PTEN by micoRNAs and ceRNAs. Other chapters present methods describing novel techniques to detect PTEN localization and previously unstudied structural features of PTEN measured through X-Ray Crystallography and Hydrogen Deuterium Exchange Mass Spectrometry. The book concludes with methods to study PTEN function in model organisms including mice and C. elegans. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and thorough, PTEN: Methods and Protocols is a valuable collection of methodologies and protocols useful to researchers who are interested in the PTEN field.

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