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SH2 Domains

Methods and Protocols

Autor: Kazuya Machida, Bernard A. Liu

Jazyk:

Vazba: Pevná

Vydavatel: Humana Press Inc.

Dostupnost: Skladem u dodavatele

Odesíláme za 10-13 dnů

4 016 Kč

This volume covers an array of techniques available for studying SH2 domains and phosphotyrosine sig...

Informace o knize

Autor

Kazuya Machida, Bernard A. Liu

Jazyk

Angličtina

Vazba

Kniha - Pevná

Vydáno

2017

Stránek

558

EAN

9781493967605

ISBN

1493967606

Enbook ID

14277282

Vydavatel

Humana Press Inc.

Hmotnost

1259

Rozměry

178 x 254 x 35

Kompletní popis

This volume covers an array of techniques available for studying SH2 domains and phosphotyrosine signaling. The book is divided into six parts: Part I outlines the history of SH2, technology development, and cell signaling; Part II focuses on computational approaches and tools used for identification, classification, and predictions of SH2 domain binding partners; Part III details various ways to prepare the SH2 domains as experimental reagents; Part IV presents methods for structural analysis and conventional binding assays using SH2 domains; Part V describes high-throughput and proteomics approaches to aid in analyzing SH2-mediated interactions; and Part VI covers applications for SH2 domain to functional and imaging analyzes. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, SH2 Domains: Methods and Protocols is a valuable resource for computational biologists, biochemists, structural biologists, cell biologists, pathologists, and people interested in SH2 domains and phosphotyrosine signaling. Researchers who are investigating how protein interaction domain mediate specificity in signaling systems may also find this book informative.

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SH2 Domains

Methods and Protocols

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