Smart Hydrogels for Controlled Drug Release

Name: Smart Hydrogels for Controlled Drug Release
Brand: LAP Lambert Academic Publishing
SKU: 9783846544983
Price: 1651 CZK
Availability: InStock

Chitosan-Based Smart Hydrogels

Autor: Ibrahim M. El-Sherbiny

Jazyk:

Vazba: Brožovaná

Vydavatel: LAP Lambert Academic Publishing

Dostupnost: Skladem u dodavatele

Odesíláme za 8-11 dnů

1 651 Kč

Controlled drug release enhances the safety, efficacy and reliability of drug therapy. The number of...

Informace o knize

Autor

Ibrahim M. El-Sherbiny

Jazyk

Angličtina

Vazba

Kniha - Brožovaná

Vydáno

2011

Stránek

208

EAN

9783846544983

Enbook ID

06929277

Vydavatel

LAP Lambert Academic Publishing

Hmotnost

328

Rozměry

150 x 220 x 12

Kompletní popis

Controlled drug release enhances the safety, efficacy and reliability of drug therapy. The number of polymers suitable for the controlled release of viable therapeutics is quite limited due to inherent toxicity or lack of certain properties such as biodegradability. Chitosan, a non-toxic and biodegradable polymer was utilized as an ideal base polymer for the development of a series of new smart hydrogels for the use in the site-specific delivery of drugs to the gastrointestinal tract. The chitosan-based smart hydrogels were obtained particularly via three main approaches. The first approach was the incorporation of chitosan into interpenetrating networks with either a hydrophilic polymer or with hydrophilic monomers treated to bring about in situ copolymerization in presence of a crosslinking agent. The second approach was the grafting of suitable hydrophilic vinyl monomers onto chitosan followed by crosslinking. In the third strategy, chitosan was modified in such a fashion that the resulting smart hydrogels could be tailored for utilization in intestine targeted delivery of peptide and protein drugs with a potential protection of the drugs from the harsh acidity of the stomach.

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Smart Hydrogels for Controlled Drug Release

Chitosan-Based Smart Hydrogels

Informace o knize

Kompletní popis

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