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Specificity, Function, and Development of NK Cells

Name: Specificity, Function, and Development of NK Cells
Brand: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
SKU: 9783642468612
Price: 2286 CZK
Availability: InStock

NK Cells: The Effector Arm of Innate Immunity

Autor: Marco Colonna, Klas Kärre

Jazyk:

Vazba: Brožovaná

Vydavatel: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG

Dostupnost: Skladem u dodavatele

Odesíláme za 8-11 dnů

2 286 Kč

Our understanding of the function of natural killer (NK) cells has dramatically changed in recent ye...

Informace o knize

Autor

Marco Colonna, Klas Kärre

Jazyk

Angličtina

Vazba

Kniha - Brožovaná

Vydáno

2012

Stránek

248

EAN

9783642468612

ISBN

3642468616

Enbook ID

07110297

Vydavatel

Springer-Verlag Berlin and Heidelberg GmbH & Co. KG

Hmotnost

406

Rozměry

155 x 235 x 15

Kompletní popis

Our understanding of the function of natural killer (NK) cells has dramatically changed in recent years. The discovery of NK receptors specific for MHC class I molecules, and the study of the role of co-stimulatory and adhesion molecules have led to an understanding of how NK cells recognize tumor and virally infected cells that have lost expression of MHC class I molecules or have altered distribution of normal cell surface molecules. Such recognition events lead to intracellular signals which can be either stimulatory or inhibitory. This book provides an insight into how NK cells develop, how they learn to distinguish altered cells from normal cells, and into their biological role in controlling infections and tumors.