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Kniha Stem Cell Genetics for Biomedical Research Raul Delgado-Morales

Stem Cell Genetics for Biomedical Research

Past, Present, and Future

Autor: Raul Delgado-Morales
Jazyk: Angličtina
Vazba: Pevná
Vydavatel: Springer International Publishing AG
Dostupnost: Skladem u dodavatele
Odesíláme za 10-13 dnů
3 198 Kč
This book looks at where stem cell technology is presently and how it is instrumental in advancing t...

Informace o knize

Autor
Raul Delgado-Morales
Jazyk
Angličtina
Vazba
Kniha - Pevná
Vydáno
2018
Stránek
426
EAN
9783319906942
ISBN
3319906941
Enbook ID
19251153
Vydavatel
Springer International Publishing AG
Hmotnost
6514
Rozměry
155 x 235 x 29

Kompletní popis

This book looks at where stem cell technology is presently and how it is instrumental in advancing the field of disease modeling and cell transplantation. By focusing on major human disorders such as Alzheimer's disease, cancer, and heart disorders, the book will summarize the major findings in the field of human stem cells and dissect the current limitations on our understanding of stem cells biology. The chapters will focus on the genetics, genomics, epigenetics and physiology of stem cells models, together with technological advances on molecular biology such as CRISPR/Cas9 or epigenetic editing, that will be instrumental in the future of human disease modeling and treatment. In base of the limitations of current disease models and in front of the unmet necessity of finding therapeutical interventions for human disorders, the availability of stem cell technology has opened new doors for several fields. The unlimited self-renewal capacity and more extensive differentiation potential of stem cells offers a theoretically inexhaustible and replenishable source of any cell subtype. Since Professor Shinya Yamanaka described it, 10 years ago in his seminal paper, that somatic cells could be reprogrammed to inducible stem cells (iPSC) just by expressing four transcription factors, the field of has exploded, especially its applications in biomedical research.

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