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Steroid Receptor Methods

Name: Steroid Receptor Methods
Brand: Humana Press Inc.
SKU: 9781617371707
Price: 2543 CZK
Availability: InStock

Protocols and Assays

Autor: Benjamin A. Lieberman

Jazyk:

Vazba: Brožovaná

Vydavatel: Humana Press Inc.

Dostupnost: Skladem u dodavatele v malém množství

Odesíláme za 13-18 dnů

2 543 Kč

A distinguished team of principal investigators and their associates describe in step-by-step detail...

Informace o knize

Autor

Benjamin A. Lieberman

Jazyk

Angličtina

Vazba

Kniha - Brožovaná

Vydáno

2010

Stránek

381

EAN

9781617371707

ISBN

161737170X

Enbook ID

01431902

Vydavatel

Humana Press Inc.

Hmotnost

581

Rozměry

152 x 229 x 22

Kompletní popis

A distinguished team of principal investigators and their associates describe in step-by-step detail a cross-section of the latest research techniques available for studying the endocrine system. As a basis for sophisticated biochemical analysis of receptor properties, the contributors provide methods for the production and purification of a variety of receptors, including progesterone, glucocorticoid, and androgen. Other protocols allow the reader to experiment with DNA binding characteristics, hormone binding assays, and the use of combinatorial chemistry for drug discovery. A series of novel methods utilizing the latest advances in immunochemistry, yeast two-hybrid screening, and fluorescence are included for the detection and analysis of a variety of cellular proteins that influence steroid receptor effectiveness.Research into steroid receptor biology holds great promise for the treatment of cancer and endocrine disorders and for elucidating the fundamental biological mechanisms of gene expression. In Steroid Receptor Methods: Protocols and Assays, a distinguished team of principal investigators and their associates describe in step-by-step detail a cross-section of the latest research techniques available for studying the endocrine system. As a basis for sophisticated biochemical analysis of receptor properties, the contributors provide methods for the production and purification of a variety of receptors, including progesterone, glucocorticoid, and androgen. Other protocols allow the reader to experiment with DNA-binding characteristics and hormone-binding assays and with the use of combinatorial chemistry for drug discovery. A series of novel methods utilizing the latest advances in immunochemistry, yeast two-hybrid screening, and fluorescence are included for the detection and analysis of a variety of cellular proteins that influence steroid receptor effectiveness. Finally, a discussion by example presents the most current bioinformatics tools and analytical techniques.§Timely and highly accessible, Steroid Receptor Methods: Protocols and Assays provides biochemists and molecular biologists studying endocrine systems with a full range of the powerful tools needed for elucidating protein interactions with receptors and DNA, as well as for drug discovery.