Kniha The CD38 molecule Ahlem Mokrane

The CD38 molecule

Autor: Ahlem Mokrane
Jazyk: Angličtina
Vazba: Brožovaná
Dostupnost: Skladem u dodavatele
Odesíláme za 8-11 dnů
572
CD38 is a transmembrane glycoprotein type II, which is expressed on normal hematopoietic cells and i...

Informace o knize

Jazyk
Angličtina
Vazba
Kniha - Brožovaná
Vydáno
2018
Stránek
84
EAN
9786138339779
Enbook ID
19185748
Hmotnost
143
Rozměry
150 x 220 x 5

Kompletní popis

CD38 is a transmembrane glycoprotein type II, which is expressed on normal hematopoietic cells and in non-hematopoietic tissues. Notably, CD38 is highly expressed in multiple myeloma, chronic lymphocytic leukemia, and other diseases. CD38 plays several roles, including ectoenzyme, receptor, adhesion molecule, and is involved in signal transduction. The cytotoxic mechanisms of daratumumab, which is considered a new high affinity human therapeutic mAb against a single CD38 epitope. CD38 represents a promising target for mAb-based immunotherapy, which has already and will continue to transform the treatment landscape into diseases, including multiple myeloma.

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