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Molecular Targeted Radiosensitizers: Opportunities and Challenges IntroductionTranslating targeted radiosensitizers into the clinic [include focus on normal tissue toxicityMechanisms and markers of clinical radioresistancePre-clinical screening of targeted radios ...
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Podrobné informace Více informací ISBN 9783030497033 Autor Willers Henning Vydavatel Humana Pr Vazba Paperback Rok vydání 2021 Počet stran 364
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Introduction Translating targeted radiosensitizers into the clinic [include focus on normal tissue toxicityMechanisms and markers of clinical radioresistance Pre-clinical screening of targeted radiosensitizers 3D radiation biology for studying radiosensitizers In vivo determinations of local tumor control and radiosensitzers GEMMs for studying radiosensitizers Pre-clinical models for studying radioresistance of GBM [include focus on PD/PK] Targeting the DNA damage response for radiosensitization [include focus on scheduling]Targeting metabolomics to overcome radioresistance Targeting cancer stem cells to overcome radioresistance Genomic biomarkers of radiation response Targeting the microenvironment Radiosensitizers in the era of immuno-oncology