Kniha Clostridium difficile K. Aktories

Clostridium difficile

Jazyk: Angličtina
Vazba: Pevná
Dostupnost: Skladem u dodavatele
Odesíláme za 10-13 dnů
3 426
Clostridium difficile has been recognized as the cause of a broad spectrum of enteric disease rangin...

Informace o knize

Jazyk
Angličtina
Vazba
Kniha - Pevná
Vydáno
2000
Stránek
150
EAN
9783540672913
ISBN
3540672915
Enbook ID
01567319
Hmotnost
910
Rozměry
155 x 235 x 13

Kompletní popis

Clostridium difficile has been recognized as the cause of a broad spectrum of enteric disease ranging from mild antibiotic-associated diarrhea to pseudomembranous colitis. This volume gives new insights into the microbiology, diagnostics and epidemiology of Clostridium difficile and describes recent strategies in treatment of diseases caused by this agent. Main parts of the volume are devoted to Clostridium difficile toxins A and B which are the major virulence factors. The molecular biology, biochemistry, pharmacology and cell biology of these toxins which are the prototypes of a new family of large clostridial cytotoxins is described in great detail. Clostridium difficile toxins act as glucosyltransferases to inactivate small GTP-binding proteins of the Rho family which are involved in regulation of the actin cytoskeleton, cell adhesion and various signaling processes.

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