Clostridium difficile

Name: Clostridium difficile
Brand: Springer, Berlin
SKU: 9783642086687
Price: 3426 CZK
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Autor: K. Aktories, T.D. Wilkins

Jazyk:

Vazba: Brožovaná

Vydavatel: Springer, Berlin

Dostupnost: Skladem u dodavatele

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Clostridium difficile has been recognized as the cause of a broad spectrum of enteric disease rangin...

Informace o knize

Autor

K. Aktories, T.D. Wilkins

Jazyk

Angličtina

Vazba

Kniha - Brožovaná

Vydáno

2010

Stránek

146

EAN

9783642086687

ISBN

3642086683

Enbook ID

01653639

Vydavatel

Springer, Berlin

Hmotnost

254

Rozměry

155 x 235 x 8

Kompletní popis

Clostridium difficile has been recognized as the cause of a broad spectrum of enteric disease ranging from mild antibiotic-associated diarrhea to pseudomembranous colitis. This volume gives new insights into the microbiology, diagnostics and epidemiology of Clostridium difficile and describes recent strategies in treatment of diseases caused by this agent. Main parts of the volume are devoted to Clostridium difficile toxins A and B which are the major virulence factors. The molecular biology, biochemistry, pharmacology and cell biology of these toxins which are the prototypes of a new family of large clostridial cytotoxins is described in great detail. Clostridium difficile toxins act as glucosyltransferases to inactivate small GTP-binding proteins of the Rho family which are involved in regulation of the actin cytoskeleton, cell adhesion and various signaling processes.

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